ECM Series — ECM Soft Tissue Bioscaffold (ECM Powder & ECM Sponge)
ECM powder and ECM sponge for ECM soft tissue repair: the ECM Antibacterial Powder is spread or packed onto the wound, and the ECM Sponge fills soft-tissue cavities — both accelerate healing, inhibit infection, fill cavities and induce regeneration
ECM Antibacterial Powder
ECM bioscaffold powder — an extracellular matrix (ECM) based antibacterial and inhibitory powder: widely used as ECM trauma dressings on infected internal/external wounds, fresh wounds, burns and crush injuries to markedly improve blood supply, accelerate healing, inhibit infection and reduce complications; it is also an ECM hemostatic material that stops capillary bleeding. How to use: after debridement, take a small amount of powder with forceps and apply to the wound surface, moisten with saline (moist wound healing) and bandage; apply once every 5 days — daily debridement is not required.
ECM Sponge
ECM filling sponge and ECM cavity-filling biomaterials: for internal soft-tissue cavity filling, providing long-lasting space occupation and inducing regeneration to achieve a soft-tissue graft effect; also an ideal ECM Tumor Filling Material for dead-space repair after tumor resection, and a routine companion to ECM trauma dressings in cavity and fistula wounds.
Antibacterial Artificial Bone Series — Antibacterial Bone Graft Materials / Artificial Bone · ECM Bioscaffold
Antibacterial bone graft materials for limb-bone bioregeneration and alveolar bone filling: induce osteogenesis, provide a sustained antibacterial effect and achieve a bone-graft effect
Antibacterial Artificial Bone Type I (Powder)
ECM artificial bone material in powder form — an ECM regenerative bone material and ECM bone repair material: for fresh fracture surgery and periodontal GTR / GBR guided regeneration, inducing osteogenesis and providing a sustained antibacterial effect.
Antibacterial Artificial Bone Type I (Granules)
Alveolar bone filling material for dental applications, periodontal regeneration, alveolar bone reconstruction after extraction and bone-graft (ECM bone transplanted materials) procedures; induces autologous bone regeneration, works as a hemostatic material, inhibits infection and fills defects for a bone-graft effect.
Antibacterial Artificial Bone Type II
Large-size dental ECM artificial bone material and alveolar bone filling material: periodontal regeneration, GBR guided bone regeneration and alveolar bone reconstruction after extraction; more economical for multiple teeth and repeated surgeries.
Antibacterial Artificial Bone Type III
Limb-bone ECM regenerative bone material for fresh fracture surgery with obvious bone defects; an ECM implanted bone material that fills the defect and induces osteogenesis with a sustained antibacterial effect, achieving a bone-graft effect.
Artificial Bone Plus Type I
ECM bioscaffold and extracellular matrix bone repair material: fills bone defects in old fracture revision surgery, inducing osteogenesis with better activity, for ECM regenerative bone material and bone-graft procedures.
Artificial Bone Plus Type II
Large-size ECM bioscaffold and ECM implanted bone material: fills large bone defects in old fracture revision surgery, inducing osteogenesis with better activity.
Biosynthetic Hernia Mesh Series — Absorbable Hernia Repair Piece / Hernia Mesh · Biological Patch
Absorbable hernia repair piece and biological patch: the Biosynthetic Hernia Mesh and the Artificial Skin are implanted as a biological patch for internal hernia surgery and thoracic repair — biodegradable, with no long-term foreign-body sensation
Biosynthetic Hernia Mesh (5×6cm)
Biosynthetic Absorbable Hernia Mesh — a biological hernia patch and absorbable hernia patch in one implant: for internal hernia surgery and thoracic repair; biodegradable, fully rebuilding the hernia region without long-term foreign-body sensation; drainage is recommended.
Biosynthetic Hernia Mesh (7×9cm)
Large-size biological hernia patch / absorbable hernia patch: for large or recurrent hernias, internal hernia surgery and thoracic repair, full reconstruction with no long-term foreign-body sensation.
Biosynthetic Artificial Skin (6×8cm)
Artificial skin and ECM trauma dressing for external skin grafts: provides a barrier and induces regeneration, creating a good regenerative environment for subcutaneous tissue in burns and large-area skin loss.
Bio-Guided Regeneration Membrane Series — Regeneration Guide Isolation Film (GTR / GBR) · Regeneration Barrier Membrane · Anti-Adhesion Membrane / Corneal Patch
Regeneration guide isolation film in GTR / GBR form — the GTR isolation membrane and GBR barrier membrane: dental guided regeneration, corneal patch, dura mater patch, craniotomy membrane, periosteum and anti-adhesion membrane — multiple sizes, single- and double-layer.
Bio-Guided Regeneration Membrane (2×2cm)
Corneal patch: for milder artificial corneal repair (sequestrum, perforation, ulcer, infection); fast degradation and quick post-op recovery, so it is also the thinnest regenerative isolation membrane in the series.
Bio-Guided Regeneration Membrane (2×3cm)
Double-layer GTR isolation membrane and GBR barrier membrane — a regenerative barrier membrane for dental guided tissue regeneration (GTR) and guided bone regeneration (GBR), plus more severe artificial corneal repair (sequestrum, perforation, ulcer, infection); slower degradation but better tension.
Bio-Guided Regeneration Membrane (3×4cm)
Double-layer regenerative isolation membrane: dental GTR / GBR barrier membrane and neurosurgical spinal dura mater patch; also used as an anti-adhesion membrane to reduce intestinal anti-adhesion after abdominal surgery.
Bio-Guided Regeneration Membrane (5×8cm)
Large-size regenerative barrier membrane: craniotomy membrane and dura mater patch for cranial and spinal repair (also usable as a neurosurgery mask), periosteum (periosteal patch) for severe bone defects, and an anti-adhesion membrane for intestinal anti-adhesion.
Clinical Application Scenarios
Quickly match ECM Regenerative Materials by department and procedure — every application below is also used in veterinary practice, in dogs and cats as well as in human surgery
🐾 Veterinary · Pet Surgical Repair
ECM materials for small-animal surgery: wound and abscess cavities after debridement, corneal ulcers and perforations, fracture gaps and bone defects, ear hematomas, hernia repair and tumour-resection dead space. These are veterinary surgical materials used by the treating veterinarian. Owners: see the pet health guides.
🩹 Trauma · Soft-Tissue Regeneration
Traumatic wounds such as bites, burns, car-crash crush injuries and skin-muscle separation: after debridement, lightly sprinkle or pack ECM Antibacterial Powder (ECM Inhibitory Powder) as ECM trauma dressings to inhibit infection and accelerate granulation and vascularization; combine with the ECM filling sponge in cavity wounds to achieve in-situ soft-tissue regeneration. Owners: see the dog wound care guide.
🎯 Oncology · ECM Tumor Filling Material
Dead-space repair after tumor resection: the ECM Sponge serves as ECM Tumor Filling Material, providing long-lasting space occupation and inducing regeneration for a soft-tissue graft effect.
🦷 Dental Consumables · Periodontal Regeneration & Alveolar Bone Regeneration
Periodontal disease with swollen and inflamed gums, and the bone defect left after extraction, are handled the same way: site preservation surgery. For alveolar bone filling — alveolar bone regeneration and alveolar bone reconstruction after extraction — choose Antibacterial Artificial Bone Type I (Granules) or Type II first; then combine periodontal GTR guided regeneration and GBR guided bone regeneration with a GTR isolation membrane or a GBR barrier membrane. Subgingival regeneration, periodontal tissue regeneration and GTR tooth preservation are the three core periodontal indications.
🦴 Orthopedics · Limb-Bone Bioregeneration Material
Limb-bone bioregeneration products: use Antibacterial Artificial Bone powder form / block Type III for fresh fractures; use Artificial Bone Plus (ECM bioscaffold) for old fracture revision and bone-defect filling.
🩹 Hernia & Thoracic · Absorbable Hernia Mesh
Biosynthetic Absorbable Hernia Mesh is used for internal hernia surgery and thoracic repair: biodegradable, fully rebuilding the hernia region without long-term foreign-body sensation; drainage is recommended.
👁️ Ophthalmology · Corneal Patch
Milder artificial corneal repair (sequestrum, perforation, ulcer, infection) uses membrane (22) with fast degradation; more severe cases use the double-layer membrane (23) with better tension.
🧠 Neurosurgery · Barrier Patch
For a dura mater patch (cranial and spinal) in craniotomy, choose Regeneration Barrier Membrane (34/58): it works as a craniotomy membrane and a neurosurgery mask for dural covering, and can also serve as a periosteum (periosteal patch) in severe bone-defect repair.
🦷 Oral Surgery · GTR / GBR Regenerative Membrane & Fistula Filling
Guided tissue regeneration and guided bone regeneration: use the GTR isolation membrane or GBR barrier membrane as a regenerative isolation membrane to exclude fast-growing soft tissue and hold the graft space in periodontal regeneration and implant procedures — this is how GTR tooth preservation is achieved; the GBR regeneration membrane is also the material of choice when bone graft material must be covered. For oronasal fistula and facial fistula repair, pack the fistula tract with ECM Antibacterial Powder and ECM Sponge before the flap suture.
🩺 Abdominal Surgery · Anti-Adhesion Membrane
Intestinal anti-adhesion: the Bio-Guided Regeneration Membrane is used as an anti-adhesion membrane after abdominal and intestinal surgery, separating the bowel from the abdominal wall and reducing adhesion formation; it can be trimmed to size on site.
Case Gallery
Six selected cases from “Amazing ECM Clinical Case Sharing” — 39 cases in total, covering soft-tissue wound regeneration, bone tissue regeneration, dental regeneration (site preservation surgery, alveolar bone regeneration and alveolar bone reconstruction, periodontal GTR guided regeneration, subgingival regeneration, oronasal fistula), hernia and chest-wall repair, artificial skin, corneal patch, dura mater patch and neurosurgery. View all 39 cases →
Featured Cases · ECM Antibacterial Powder / ECM Sponge / Antibacterial Artificial Bone / Hernia Mesh / Regeneration Barrier Membrane
Bite-Wound Regeneration
After debridement and irrigation of the bitten, ulcerated wound, ECM Antibacterial Powder (ECM Inhibitory Powder) was placed on the wound, moistened with saline and bandaged with gauze. Re-check one week later showed the wound markedly reduced, with normal soft-tissue and surrounding-skin regeneration, no infection and no premature scabbing.
Large-Area Burn (approx. 40cm)
An adult cat with an approx. 40cm large-area burn on its side. ECM Antibacterial Powder was first applied on Sep 11, 2024; after 5 days the wound was markedly reduced with no infection. Areas hard to bandage were fixed with skin staples or a stitch at each corner. The wound kept shrinking with each application and gradually recovered after Oct 8.
Old Comminuted Fracture Revision
A third revision surgery for severe comminuted, infected fracture with very large bone defect; Artificial Bone Plus (ECM bioscaffold with added BMP) was used together with a periosteal patch — isolating soft tissue to prevent premature invasion and forming early periosteum through vascularization to nourish osteogenesis. Eventually the plate was removed and movement recovered as before.
Periodontal GTR Guided Regeneration (Tooth-Saving)
A 10-year-old dog with severe periodontal disease and alveolar bone atrophy; the owner declined multiple extractions and chose GTR tooth-saving surgery: mucosal flap reflection, extraction of the periapical-periodontitis tooth, root planing and repeated curettage, Antibacterial Artificial Bone granules packed and covered with Regeneration Barrier Membrane (smooth side inward), tension-free nodular suturing, and “button” principle to tighten the periodontal space around the canine. At 10-day suture removal tooth stability was better, with good follow-up.
Thoracic Cavity Repair
Bite wounds on both rib sides created two holes that soft tissue could not suture; hernia mesh was used for repair. As the area was too large, two pieces were pieced together; where the seam leaked, another mesh piece was overlaid and sutured in a “patching” fashion, with good post-op recovery.
Hemilaminectomy (Disc Fenestration)
During neurosurgical hemilaminectomy, the ECM membrane sheet (Regeneration Barrier Membrane) was applied as a barrier and regeneration scaffold to protect neural tissue.
View All 39 Clinical Cases
Complete case gallery with 132 clinical photographs and 29 surgical videos — soft-tissue wound regeneration · bone tissue regeneration · dental regeneration (alveolar bone reconstruction, periodontal GTR) · hernia and chest-wall repair · artificial skin, corneal patch, dura mater patch and neurosurgery.
Open Case Gallery →FAQ
Common Questions about ECM Regenerative Materials
What is an ECM Bioscaffold?
The ECM bioscaffold is a biological regeneration material based on decellularized extracellular matrix (ECM), retaining natural 3D structure and bioactivity, providing a scaffold and microenvironment for tissue regeneration and guiding the body's own tissue to regenerate.
What is the difference between ECM Antibacterial Powder, ECM Inhibitory Powder and ECM Regenerative Powder?
All three refer to ECM Antibacterial Powder (different names). As a surgical companion, it is widely used on various infected internal/external wounds and fresh wounds to improve blood supply, accelerate healing and inhibit infection.
Which dental consumable for periodontal regeneration and alveolar bone regeneration?
Periodontal disease with swollen and inflamed gums, subgingival regeneration and periodontal tissue regeneration all need the defect filled and isolated. For alveolar bone filling and alveolar bone regeneration we recommend Antibacterial Artificial Bone Type I (Granules) — periodontal regeneration after extraction, alveolar bone reconstruction and site preservation surgery — or Type II (large size, more economical); add a GTR isolation membrane for GTR tooth preservation, and choose Artificial Bone Plus (ECM bioscaffold) for revision and reconstruction.
Can ECM materials be used for oronasal fistula and facial fistula repair?
Yes. An oronasal fistula forms not only in unextracted teeth but also commonly after extraction when suturing is improper, and the same defect can open into a facial fistula. Cut the ECM Sponge to size and pack the fistula tract as an ECM filling sponge, then do a tension-free flap suture hooking the sponge with a few stitches so it cannot be inhaled into the nasal cavity; the sponge is fully replaced by soft tissue and closes the fistula. ECM Antibacterial Powder is sprinkled in first to control infection and bleeding.
Features of the Biosynthetic Absorbable Hernia Mesh?
Biodegradable, fully rebuilding the hernia region without long-term foreign-body sensation; suitable for internal hernia surgery and thoracic repair, with drainage recommended; sizes 50×60mm and 70×90mm.
What is the difference between a GTR membrane and a GBR membrane?
GTR (guided tissue regeneration) and GBR (guided bone regeneration) both rely on a regenerative isolation membrane that keeps fast-growing soft tissue out of the defect. GTR is the periodontal indication: a GTR isolation membrane or GTR barrier membrane is placed between the gingival flap and the root surface. GBR is the bone-site indication: a GBR barrier membrane or GBR regeneration membrane covers the bone defect and holds the graft material and the space. Our Bio-Guided Regeneration Membrane covers both: use the 20×30mm and 30×40mm double layer as a GTR regenerative membrane in periodontal surgery, and the 30×40mm and 50×80mm as a GBR barrier membrane in alveolar bone reconstruction.
ECM silver ion dressings vs ECM chitosan dressings vs ECM Antibacterial Powder — which should I choose?
ECM silver ion dressings and ECM chitosan dressings work mainly through the antimicrobial agent the dressing carries. The ECM Antibacterial Powder (ECM Inhibitory Powder) works differently: it is a decellularized extracellular matrix biomaterial that provides a scaffold and a microenvironment, so the tissue regenerates in place while infection is inhibited. For infected and non-healing wounds, the ECM powder can be combined with a silver ion or chitosan dressing when a stronger topical antimicrobial action is needed.
What is the Bio-Guided Regeneration Membrane used for?
It is the barrier and anti-adhesion product line. As a regenerative barrier membrane it covers periodontal and bone defects (GTR / GBR) and acts as an anti-adhesion membrane against intestinal anti-adhesion after abdominal surgery. By thickness: the 20×20mm single layer is a corneal patch; the double-layer 20×30mm, 30×40mm and 50×80mm act as a dura mater patch, a craniotomy membrane, a periosteum (periosteal patch) and, in larger defects, a neurosurgery mask.
What scenarios is the ECM Cavity-Filling Sponge suitable for?
The ECM Sponge is an ECM cavity-filling material used for internal soft-tissue cavity filling, providing long-lasting space occupation and inducing regeneration to achieve soft-tissue graft effect; it can also serve as ECM Tumor Filling Material for dead-space repair after tumor resection, as well as orbital filling after enucleation and epidural space filling.
Pet Health Guides — ECM in Veterinary Surgery
Practical guides for pet owners written around the questions people actually search for: what to do at home, what not to do, when to call the vet, and how veterinary clinics treat the wounds that will not close
Dog Wound Care
First aid in the first ten minutes, how to clean a dog wound at home, choosing a dressing and bandage, infection signs, healing stages and when to call the vet.
Dog Abscess
Why an abscess is a walled-off pocket of pus, which ones are an emergency, how a vet drains the cavity, and why an abscess cavity must not simply be stitched shut.
Dog Hot Spots
The raw, weeping skin lesion that appears overnight: what triggers acute moist dermatitis, how it is treated, and what to do when the surface breaks down.
Dog Skin Infection
Bacterial, yeast, fungal and parasitic skin infection — how they differ, how a vet confirms the diagnosis, and why some dogs keep re-infecting.
Dog Surgery Recovery
Post-operative incision care day by day: normal versus abnormal swelling, seromas, stitch and drain timings, activity restriction and warning signs.
Dog Fracture
How to recognise a fracture, what to do in the first thirty minutes, what a splint can and cannot fix, the week-by-week bone healing timeline, and why some fractures never unite.
Dog Hernia
Which hernias can be watched and which are emergencies, how vets diagnose and repair each type, and when a reinforcing mesh is needed instead of simple suturing.
Dog Eye Infection
Red eye, discharge and squinting: which signs mean the dog must be seen today, why human eye drops are dangerous, and how a damaged cornea is repaired.
Dog Tooth Extraction
Why most extractions happen, what the empty socket needs, how the alveolar bone is rebuilt, and how oronasal fistula is prevented.
Dog Lump: Abscess, Cyst or Tumour?
A lump on a dog has many causes and they feel alike. Which lumps need surgery soon, why the needle aspirate settles the question, and what removal leaves behind.
Dog Corneal Ulcer
An ulcer is a hole in the surface of the eye. What the fluorescein stain shows, how depth decides the treatment, healing time, and how a damaged cornea is rebuilt.
Dog Periodontal Disease
Most dogs have it by age three. The four stages and which one reverses, what professional cleaning involves, what home care works, and how a tooth is saved with GTR.
Dog Ear Infection
Why an ear infection keeps coming back, how vets separate bacterial from yeast otitis, and when a chronically narrowed ear canal finally needs surgery.
Itchy Skin in Dogs
Constant scratching is a symptom, not a diagnosis. The causes vets check in order, how the itch-scratch cycle damages skin, and what actually stops the itch.
Scabs and Crusts on a Dog
What a normal scab looks like, what black and yellow crusts mean, why some wounds never scab, and why vets keep wounds moist on purpose.
Dog Ear Hematoma
Why the ear flap fills with blood after violent head shaking, whether it can heal alone, and how the cavity left by surgery is closed and supported.
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